Then you may be interested in the SPOTLIGHT study. It will test how well an investigational drug works and how safe it is. This website will tell you what you need to know about being in the study.
To learn more, click one of the buttons.
Adults with newly diagnosed locally advanced unresectable or metastatic gastric or gastroesophageal junction (GEJ) cancer who:
This website is for US residents only. Residents outside the US please go to clinicaltrials.gov for more information.
A Phase 3 efficacy, safety and tolerability study of zolbetuximab (experimental drug) plus mFOLFOX6 chemotherapy compared to placebo plus mFOLFOX6 as treatment for gastric and gastroesophageal junction (GEJ) cancer
Please note that if you decide to participate in the study you can also choose to stop at any time.
Participating in a study requires time and effort for you and your caregivers. Below is important information about the number of visits you can expect during the SPOTLIGHT study period should you decide to participate:
Cycles depending upon
The main purpose of the SPOTLIGHT Study is to gather information about the investigational study drug, zolbetuximab (IMAB362), to see if it is effective in people with locally advanced unresectable or metastatic gastric or GEJ cancer when used in combination with an approved cancer treatment called mFOLFOX6.
Zolbetuximab or placebo, in combination with mFOLFOX6 (fluorouracil, leucovorin, oxaliplatin)
Being part of the SPOTLIGHT study takes time and effort for the person participating and their caregiver. You may:
This drug is experimental. Because of that, not all risks are known before starting a clinical trial. People who are in the study may stop at any time.
Based on your answers, you may be a good candidate for this study.
To find the clinical trial center closest to you, enter your location below.
The clinical trial center will determine your eligibility for participation in this study.
Based on your answers, this study may not be right for you. Please talk to your doctor if you still have questions about the SPOTLIGHT study. Or, if you still think you may be a good candidate for this clinical trial, search below for a clinical trial center near you.